Brain Basics

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To understand aneurysms, it is beneficial to understand the circulatory system of the brain.  Blood is carried to the brain by two paired arteries, the internal carotid arteries and the vertebral arteries.

Cerebral Circulation - Brain Basics

The internal carotid arteries supply the anterior (front) areas and the vertebral arteries supply the posterior (back) areas of the brain.  After passing through the skull, the right and left vertebral arteries join together to form a single basilar artery. The basilar artery and the internal carotid arteries “communicate” with each other in a ring at the base of the brain called the Circle of Willis.

Cerebral circulation

Cerebral circulation is the movement of blood through the network of blood vessels supplying the brain. The arteries deliver oxygenated blood, glucose and other nutrients to the brain and the veins carry deoxygenated blood back to the heart, removing carbon dioxide, lactic acid, and other metabolic products. Since the brain is very vulnerable to compromises in its blood supply, the cerebral circulatory system has many safeguards. Failure of these safeguards results in cerebrovascular accidents, commonly known as strokes. The amount of blood that the cerebral circulation carries is known as cerebral blood flow. The presence of gravitational fields or accelerations also determine variations in the movement and distribution of blood in the brain, such as when suspended upside-down.
Arterial Circulation - Brain Basics

Arterial cerebral circulation

The arterial cerebral circulation is normally divided into anterior cerebral circulation and posterior cerebral circulation. There are two main pairs of arteries that supply the cerebral arteries and the cerebrum: Internal carotid arteries and vertebral arteries.

The anterior and posterior cerebral circulations are interconnected via bilateral posterior communicating arteries. They are part of the Circle of Willis, which provides backup circulation to the brain. In case one of the supply arteries is occluded, the Circle of Willis provides interconnections between the anterior and the posterior cerebral circulation along the floor of the cerebral vault, providing blood to tissues that would otherwise become ischemic.

Anterior cerebral circulation

The anterior cerebral circulation is the blood supply to the anterior portion of the brain. It is supplied by the following arteries:

  • Internal carotid arteries: These large arteries are the left and right branches of the common carotid arteries in the neck which enter the skull, as opposed to the external carotid branches which supply the facial tissues. The internal carotid artery branches into the anterior cerebral artery and continues to form the middle cerebral artery
  • Anterior cerebral artery (ACA)
    • Anterior communicating artery: Connects both anterior cerebral arteries, within and along the floor of the cerebral vault.
  • Middle cerebral artery (MCA)

Posterior cerebral circulation

The posterior cerebral circulation is the blood supply to the posterior portion of the brain, including the occipital lobes, cerebellum and brainstem. It is supplied by the following arteries:

  • Vertebral arteries: These smaller arteries branch from the subclavian arteries which primarily supply the shoulders, lateral chest and arms. Within the cranium the two vertebral arAneurysm Locations - Brain Basicsteries fuse into the basilar artery.
  • Posterior inferior cerebellar artery (PICA)
  • Basilar artery: Supplies the midbrain, cerebellum, and usually branches into the posterior cerebral artery
  • Anterior inferior cerebellar artery (AICA)
  • Pontine branches
  • Superior cerebellar artery (SCA)
  • Posterior cerebral artery (PCA)
  • Posterior communicating artery

 Frequent aneurysm locations

  • Internal carotid artery
  • Middle cerebral artery
  • Anterior cerebral artery
  • Basilar artery
  • Vertebral basilar
  • Posterior communicating artery
  • Cavernous carotid artery

Brain arteries

These are the pipes that transport blood pumped by your heart to your brain.  As you can imagine, they are lined with a muscular layer to help maintain the pressure of the blood so that the furthest regions of your brain can get a steady stream of blood.  The cells that make up the wall of the artery are not static.  In fact, these cells are constantly growing and remodeling in response to the pressure from the blood within it to attempt to maintain, as much as possible, a smooth cylindrical shape.

Brain veins

Veins are thin walled vessels which lack a muscular wall that drain blood after it has passed through tissues or organs.  After they have passed through tissues or organs, they lose oxygen and are under very little pressure as it returns it to the heart to get pumped to the lungs.  Veins outside the brain are usually more visible as blue vessels near the skin surface.

To highlight our impact and convey our mission with clarity, we are excited to announce that the Joe Niekro Foundation is now the Niekro Aneurysm and AVM Foundation. We look forward to building on the Niekro legacy and continuing our mission!
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